Mixturs of quaternary ammonium compounds and long-chain fatty acids as antifungal agents.
نویسندگان
چکیده
The influence of undecylenic acid on the fungistatic effect of phenoxyethyldimethyldodecylammonium bromide (Domiphen bromide) against Trichophyton mentagrophytes was investigated. The unsaturated fatty acid was found to enhance the fungistatic activity of Domiphen bromide against this organism. The ratio of concentrations of these agents has a marked influence on the results of in vitro tests for antifungal action resulting in a completely different effect than heretofore noted in combination experiments against bacteria. The enhancing phenomenon is not particular to T. mentagrophytes, it was observed also with Candida albicans.
منابع مشابه
Mixtures of Quaternary Ammonium Compounds and Long-chain Fatty Acids as Antifungal Agents
KULL, F. C. (CIBA Pharmaceutical Products Inc., Summit, N. J.), P. C. EISMAN, H. D. SYLWESTROWICZ, AND R. L. MAYER. Mixtures of quaternary ammonium compounds and long-chain fatty acids as antifungal agents. Appl. Microbiol. 9:538-541. 1961.-The influence of undecylenic acid on the fungistatic effect of phenoxyethyldimethyldodecylammonium bromide (Domiphen bromide) against Trichophyton mentagrop...
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ورودعنوان ژورنال:
- Applied microbiology
دوره 9 شماره
صفحات -
تاریخ انتشار 1961